Translating painting’s visual language into architectural space offers an interdisciplinary means of generating design ideas. However, formal resemblance between an artwork and a building does not, in itself, establish influence or demonstrate a process of translation. This study investigates how three components of painting—color, form, and structure—can be transformed into architectural spatial strategies. It adopts a qualitative approach based on comparative analysis of multiple cases. Six painting–architecture pairs were purposively selected according to defined criteria. The analysis focuses on the logic of visual organization in painting and the strategy of spatial organization in architecture.The findings show that visual translation moves beyond formal imitation when an artwork’s surface characteristics are reconfigured as organizing relationships. Color, for example, can inform the organization of atmosphere and light; geometry can guide the arrangement of volume and movement; and visual rhythm can be translated into spatial sequence and order. Drawing on cross-case comparison, the study proposes a six-stage framework: observation, extraction of visual codes, relational abstraction, transformation into a spatial strategy, architectural testing, and assessment of innovation. The framework offers an analytical tool for interdisciplinary research on art and architecture, as well as an initial guide for generating ideas in the design process.